人毛囊外根鞘细胞描述:
毛囊外壳环绕毛发纤维周围或在根鞘内部。它与其它上皮成分不同,与表皮连接。毛囊外壳由具有独特的结构特性的几层细胞组成,对毛囊起着重要的作用,例如做为感应器官和皮肤的免疫防卫。免疫组织化学染色表明毛囊外壳包含嵌入式表达前体或干细胞。人类外根鞘细胞表现为重叠的角化细胞,在体外易于广泛培养。
人毛囊外根鞘细胞(HHORSC)提取于人毛囊外根鞘细胞,原代冻存。每管含有细胞数>5×105,此细胞通过Fibronectin and CD105免疫荧光染色验证,经测试不含有HIV-1、HBV、HCV、支原体、细菌、酵母和真菌。细胞可以达到10倍增。
推荐培养基:(MSCM, Cat. No. 7501)
产品使用说明:仅供科研研究使用
货号 | 2420 |
产地 | 美国 |
缩写 | HHORSC |
规格 | 5 x 10^5 cells/vial |
用途 | 科研 |
运输 | 干冰 |
保存 | 液氮 |
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2.) Panicker SP, Ganguly T, Consolo M, Price V, Mirmirani P, Honda K, Karnik P. (2012) "Sterol intermediates of cholesterol biosynthesis inhibit hair growth and trigger an innate immune response in cicatricial alopecia." PLoS One. 7: e38449.
3.) Karnik P, Tekeste Z, McCormick TS, Gilliam AC, Price VH, Cooper KD, Mirmirani P. (2009) "Hair follicle stem cell-specific PPARgamma deletion causes scarring alopecia." J Invest Dermatol. 129: 1243-57.
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